A case of type 1 achalasia associated with Parkinson's disease

Subacute sclerosing panencephalitis (SSPE) is a rare, non-treatable and fatal neurological complication of measles, still present due to the return epidemic linked loosening vaccination policies. Its mechanism remains unexplained.The main objective was investigate explanatory variables relating risk developing SSPE its pathophysiology.Literature analysis focused on different varieties SSPE: perinatal forms, short-incubation forms similar acute measles inclusion body encephalitis (MIBE), rapidly evolving occurring in immunosuppressed, adult family forms. In addition, several studies parameters innate immunity interferon responses patients were analyzed.Two data highlighted: relationship between so-called fulminant prescription corticosteroids established. familial SSPE, two groups individualized according duration latency period, prompting an patient exomes.Treatment with should be banned. Knowledge genes involved epigenetics useful for understanding pathophysiology other late-onset infections RNA viruses.